Being diagnosed with myeloma can make an already difficult situation even more confusing and scary. You might feel overwhelmed, numb, fearful, angry or frustrated. Or it might come as a relief that you finally have an answer to why you’ve felt so unwell for so long. All of these feelings are common and are a natural part of coming to terms with a diagnosis. Remember, our team of Myeloma Information Specialists are always here to talk. Find out more in our Help & support section.
How is myeloma diagnosed?
Usually, when myeloma is suspected, you’ll be referred to a haematologist – a hospital doctor who specialises in the study of blood and blood-related disorders. The doctor will arrange for some tests and investigations to find out if you do have myeloma.
There are three main tests which doctors use to confirm a myeloma diagnosis, these are:
There are a variety of blood tests which can diagnose and monitor myeloma. Regular blood tests are performed to measure your paraprotein and/or light chain level. The presence of paraprotein and/or light chains is a strong indicator of myeloma and can be used as a measure of how active it is, although not in every person. Other blood tests will also be done regularly, measuring the levels of different cells in your blood. Some of the most important are:
- Red blood cell count: a low count shows you are anaemic
- White blood cell counts: low counts of some or all of the different white blood cells indicate you are at greater risk of infection
- Platelet count: a low count shows you are at an increased risk of bleeding or bruising more easily than normal
As myeloma can thin or erode the bones, imaging tests can be important, particularly at diagnosis. A skeletal survey is a series of X-rays of the long bones, spine and the skull, to detect evidence of bone damage. More advanced imaging tests include magnetic resonance imaging (MRI) or computerised tomography (CT) scans. These scans can provide more detail and identify areas of bone damage which are not so easily detected by X-ray.
Bone marrow biopsy
This involves taking a small sample (known as a biopsy) of the bone marrow, usually from the back of the hip bone. The sample is examined under a microscope. Normal bone marrow contains less than five per cent normal plasma cells. Myeloma patients may have between 10-90 per cent abnormal plasma cells.
If your diagnosis is confirmed, some of these tests will be repeated regularly to monitor your myeloma over time.
Timely diagnosis and the Early Diagnosis Steering Committee
We are working on projects aiming to reduce time to diagnosis and we strive to increase awareness of the early signs and symptoms of myeloma, by educating GPs and other healthcare professionals. Find out about our Early Diagnosis Programme and the Myeloma UK Early Diagnosis Steering Committee.
Your prognosis and life expectancy
Myeloma is highly treatable in the majority of patients. Unfortunately, though, it is currently an incurable (terminal) cancer. There are many different factors that will affect how long a patient is likely to live.
According to the most recent statistics available, just over half (50 per cent) of myeloma patients in England will live for at least five years and a third (33 per cent) will live for at least 10 years.
It’s important to bear in mind these are only average figures. It can be difficult, if not impossible, to predict how long someone is likely to live with myeloma.